Moderna COVID-19 Vaccine Appears Safe, Shows Signs of Working in Older Adults - COVID-19 Clinical Trial
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Moderna COVID-19 Vaccine Appears Safe, Shows Signs of Working in Older Adults

Results from an early safety study of Moderna Inc’s coronavirus vaccine candidate in older adults showed that it produced virus-neutralizing antibodies at levels similar to those seen in younger adults, with side effects roughly on par with high-dose flu shots, researchers said on Tuesday. The study, published in the New England Journal of Medicine, offers a more complete picture of the vaccine’s safety in older adults, a group at increased risk of severe complications from COVID-19.

The findings are reassuring because immunity tends to weaken with age, Dr. Evan Anderson, one of the study’s lead researchers from Emory University in Atlanta, said in a phone interview. The study was an extension of Moderna’s Phase I safety trial, first conducted in individuals aged 18-55. It tested two doses of Moderna’s vaccine – 25 micrograms and 100 micrograms – in 40 adults aged 56 to 70 and 71 and older.


Serum Institute Says Will Make Additional 100 Million Covid Vaccine Doses

Serum Institute of India will make up to 200 million COVID-19 vaccine doses for poorer countries, including India, next year, as the Bill & Melinda Gates Foundation and GAVI vaccines alliance have doubled their funding, the company said on Tuesday.The extra funds will help Serum boost manufacturing of the vaccine candidates from AstraZeneca Plc and Novavax Inc, for delivery under the COVAX scheme as early as the first half of 2021.

The collaboration takes forward an initial agreement signed in August by Serum, GAVI and the Gates Foundation for 100 million doses to be priced at a maximum of $3 each.The total funding provided is now $300 million, and the expanded collaboration also has an option for the provision of additional doses as needed.

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